Beyond Stability Constraints: A Biophysical Model of Enzyme Evolution with Selection on Stability and Activity
نویسندگان
چکیده
منابع مشابه
Influence of a Novel Magnetic Recoverable Support on Kinetic, Stability and Activity of Beta-amylase Enzyme
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in this paper, covalent immobilization of beta amylase enzyme on the surface of modified magnetic nano particles (znfe2o4@sio2-nh2) is reported. for doing so, at first, the magnetic nanoparticles of znfe2o4 were synthesized by chemical co-precipitation method and then tetraethyl orthosilicate (teos) and 3-aminopropyltriethoxy silane (aptes) were used for modification of znfe2o4 nanoparticles wi...
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Model selection is linked to model assessment, which is the problem of comparing different models, or model parameters, for a specific learning task. For supervised learning, the standard practical technique is crossvalidation, which is not applicable for semi-supervised and unsupervised settings. In this paper, a new model assessment scheme is introduced which is based on a notion of stability...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2018
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msy244